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Testosterone Pellet Vs. Injection: Which Is Best for Women Facing Menopause?

October 17, 2025

A woman is holding a white pill in hand, which is a testosterone pellet for women.

Both a testosterone pellet for women and injections can effectively treat menopause symptoms, but pellets offer longer-lasting relief with fewer applications.

In short:

  • Longer-Lasting Relief – Pellets provide hormone therapy for 3-4 months compared to injections every few weeks.
  • Fewer Side Effects – Pellets maintain steadier hormone levels, reducing mood swings and energy crashes.
  • Better Convenience – Pellets require only 3-4 insertions per year versus 12-26 injections annually.

Menopause brings many challenging symptoms for women, and a testosterone pellet for women has become a popular treatment option alongside traditional injections. Understanding the differences between these two testosterone treatments can help you make an informed decision about your hormone therapy.

Let us explore testosterone injections and a testosterone pellet for women and determine which one might be right for you.

What Is Testosterone Treatment for Adults

Testosterone treatment helps replace hormones that naturally decline during andropause and menopause. While most people think of testosterone as a male hormone, women also produce it in smaller amounts.

During menopause, testosterone levels can drop significantly. This decline often leads to symptoms like low energy, decreased muscle mass, reduced bone density, and loss of sexual desire.

Testosterone for female menopause comes in several forms. The two most common delivery methods are pellets and injections, each offering unique benefits for hormone replacement therapy.

How Do Testosterone Pellets for Women Work

Testosterone pellets are tiny, rice-sized implants placed under the skin during a simple office procedure. These pellets contain bioidentical testosterone that slowly releases into your bloodstream over 3-4 months.

The pellet insertion process takes about 15 minutes. Your doctor numbs a small area on your hip or buttock, makes a tiny incision, and inserts the pellets using a special device. The incision is so small that it typically does not require stitches.

How Do Testosterone Injections Work

Testosterone injections deliver hormones directly into muscle tissue, usually in the thigh or buttock. These injections typically contain testosterone cypionate (Depo-Testosterone) or testosterone enanthate (Delatestryl).

Most women receive injections every 1-2 weeks, though some may need them more or less frequently based on their individual response. The hormone enters your bloodstream quickly, providing relief within days.

However, injection levels can fluctuate significantly. You might feel great for the first week after an injection, then experience declining energy and mood as hormone levels drop before your next dose.

Which Treatment Provides Better Results

Research comparing these two methods shows important differences in effectiveness and patient satisfaction.

A 2025 PubMed Central study stated that “Pellets help maintain more stable testosterone levels compared to other delivery methods.”

The study also mentioned that testosterone pellets were associated with significant improvements in sexual function, mood, and quality of life.

Hormone Level Consistency

Pellets maintain steadier hormone levels throughout the treatment period. This consistency means fewer symptoms and side effects for most women.

Injections create peaks and valleys in hormone levels. You might experience excellent symptom relief immediately after injection, followed by gradual worsening as levels decline.

Symptom Relief Duration

Testosterone pellets provide continuous relief for 3-4 months. Most women report consistent energy, improved mood, and better sleep throughout this period.

Injections may provide 1-2 weeks of optimal symptom relief, followed by a gradual return of symptoms until the next injection.

What Are the Side Effects

Both treatments can cause similar side effects, but the frequency and intensity often differ.

Common Side Effects for Both Methods

  • Acne or oily skin.
  • Hair growth in unwanted areas.
  • Voice deepening (rare with proper dosing).
  • Mood changes.
  • Changes in cholesterol levels.

Pellet-Specific Considerations

A testosterone pellet for women may cause minor bruising or soreness at the insertion site for a few days. Rarely, testosterone pellets for women can work their way out of the skin, requiring reinsertion.

The steady hormone release from a testosterone pellet for women typically causes fewer mood swings and energy crashes compared to injections.

Injection-Specific Considerations

Injections can cause pain, swelling, or bruising at the injection site. Some women develop scar tissue from repeated injections in the same area.

The fluctuating hormone levels from injections may cause more frequent mood changes and energy variations.

How Much Do These Treatments Cost

Treatment costs vary significantly based on location, insurance coverage, and individual hormone needs.

Many insurance plans cover testosterone treatment for medically necessary hormone replacement, but coverage varies widely.

Which Women Are Good Candidates

The best treatment choice depends on your lifestyle, symptoms, and medical history.

Good Candidates for Pellets

  • Women who want consistent hormone levels.
  • Those who prefer fewer medical appointments.
  • Women with busy schedules who might forget injections.
  • Those who experience significant mood swings with fluctuating hormone levels.

Good Candidates for Injections

  • Women who want more control over their treatment.
  • Those who prefer avoiding minor surgical procedures.
  • Women who want to adjust dosing more frequently.
  • Those with concerns about pellet insertion.

Testosterone Pellet for Women in Dallas, TX

Choosing between a testosterone pellet for women and an injection depends on your individual needs and preferences. Both treatments can effectively manage menopause symptoms when properly supervised by a qualified healthcare provider.

Ready to explore your testosterone for female menopause? Our Dr. David Fein at North Dallas Wellness Center specializes in personalized hormone therapy for women experiencing menopause. Our team is dedicated to helping women live their best lives during menopause and beyond.

Schedule a consultation to discuss whether a testosterone pellet for women or an injection is right for your unique situation and take the first step toward reclaiming your energy and vitality. Contact our friendly staff at (214) 696-3885 or use our appointment request form to schedule your consultation. We look forward to serving you!

Filed Under: Testosterone Therapy Tagged With: hormone therapy for women, manage menopause symptoms, menopause, testosterone for female menopause, testosterone levels, testosterone pellet for women, Testosterone Pellet for Women in Dallas, testosterone treatment for adults

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North Dallas Wellness Center offers wellness services - IV Vitamin Infusion Therapy , Life Extension with Rapamycin , Medical Weight Loss & Testosterone Therapy treatments - Bio-Identical Hormone Replacement Therapy , Testosterone Therapy for Men ,Testosterone Therapy for Women In North Dallas, Texas